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    The Herbert W. Boyer School of Natural Sciences, Mathematics, and Computing
    Phone: 724-805-2631
    stephen.jodis@stvincent.edu  


Home > Majors and Programs > Biology
  • Michael RhodesDr. Michael Rhodes

    Associate Professor of Biology  

    N110, Sis and Herman Dupré Science Pavilion 
    (724) 805-2360
    michael.rhodes@stvincent.edu 

    Research Interests

    Neuroendocrinology and Neuropharmacology
    Pharmacology and the Hypothalamic-Pituitary-Adrenal Axis
    Sexual Diergism (Functional Sex Differences) and Stress
    Nicotine Addiction and Withdrawal
    Environmental Enrichment

    Education

    B.S. Biology. 1993. Saint Vincent College, Latrobe, PA
    M.S. Pharmacology-Toxicology. 1995. Duquesne University, Pittsburgh, PA
    Ph.D. Pharmacology-Toxicology. 1997. Duquesne University, Pittsburgh, PA

    Courses Taught

    NSCI 200 All About Drugs
    BL 150 General Biology I
    BL 151 General Biology I Laboratory
    BL 220 Comparative Vertebrate Anatomy
    BL 221 Comparative Vertebrate Anatomy Laboratory
    BL 242 Histology
    BL 243 Histology Laboratory
    BL 301 Junior Research Seminar
    BL 302 Research Project
    BL 303 Research Thesis
    HSC 500 Advanced Pharmacology I
    HSC 501 Advanced Pharmacology II

    Peer-Reviewed Publications

    Belz E.E., Kennell J.S., Czambel R.K., Rubin, R.T., and Rhodes M.E. Environmental enrichment lowers stress-responsive hormones in singly-housed male and female rats. Pharm. Biochem. Behav. 76:481-486, 2003.

    Rhodes M.E., Kennell J.S., Belz E.E., Czambel R.K., and Rubin R.T. Rat Estrous cycle influences the sexual diergism of HPA axis stimulation by nicotine. Brain Res Bull 64:205-213, 2004.

    Rhodes M.E., Czambel R.K., and Rubin R.T. Pituitary-adrenal responses to cholinergic stimulation and acute mild stress are elevated differentially in male and female M2 muscarinic receptor knockout mice. J. Neuroendocrinol. 17:817-826, 2005.

    Moidel M.A., Belz E.E., Czambel R.K., Rubin R.T., and Rhodes M.E. Novel in vitro perfusion system for the determination of hypothalamic-pituitary-adrenal axis responses. J. Pharmacol. Toxicol. Methods. 53:264-271, 2006.

    Rubin R.T., Miller T.H., Rhodes M.E., and Czambel R.K. Growth hormone responses to low-dose physostigmine in elderly vs. young women and men. Gerontology 52:76-84, 2006.

    Rubin R.T., Miller T.H., Rhodes M.E., and Czambel R.K. Adrenal cortical responses to low- and high-dose ACTH1-24 administration in major depressives and matched controls. Psychiatry Research 143:43-50, 2006.

    Rubin R.T., Rhodes M.E., Miller T.H., Jakob R., and Czambel R.K. Sequence of pituitary-adrenal cortical hormone responses to low-dose physostigmine administration in young adult women and men. Life Sci. 79:2260-2268, 2006.

    Rhodes M.E. Adrenocorticotropic hormone (ACTH). In: Encyclopedia of Stress, 2nd Ed. George Fink (Ed.), Academic Press, Elsevier, Inc., Oxford, 2007 (ISBN: 978-0-12-088503-9).

    Rhodes M.E., McKlveen J.M., Karwoski T.E., Fulton B.A., and Czambel R.K. Pituitary-adrenal responses to oxotremorine and acute stress in male and female M1 muscarinic receptor knockout mice: comparisons to M2 muscarinic receptor knockout mice. . J. Neuroendocrinol. 20:617-625, 2008.

    Rivardo M.G., Rhodes M.E., and Klein B. Lack of stereotype threat at a liberal arts college. The College Student Journal. 42:832-841, 2008.

    Rhodes M.E., Creel T.J., and Nord A.N. Sex differences in CNS neurotransmitter influences on behavior. In: Hormones, Brain and Behavior, 2nd Edition, D. Pfaff, A.P. Arnold, A.M. Etgen, S.E. Fahrbach, R.T. Rubin (Eds.) Academic Press/Elsevier, NY, 2009, pp. 2747-2785. (ISBN-10: 0123743826).

    Rhodes M.E., McKlveen J.M., Ripepi D.R., and Gentile N.E. Hypothalamic-pituitary-adrenal cortical axis. In: Hormones, Brain and Behavior, 2nd Edition, D. Pfaff, A.P. Arnold, A.M. Etgen, S.E. Fahrbach, R.T. Rubin (Eds.) Academic Press/Elsevier, NY, 2009, pp 2319-2339. (ISBN-10: 0123743826).

    Rhodes M.E., McKlveen J.M., Ripepi D.R., and Gentile N.E. Hypothalamic-pituitary-adrenal cortical axis. In: Hormone/Behavior Relations of Clinical Importance — Endocrine Systems Interacting with Brain and Behavior, 1st Edition, R.T. Rubin & D. Pfaff (Eds.) Academic Press/Elsevier, NY, 2009. (ISBN-10: 0123749263).

    McKlveen J.M., Wilson J.M., Rubin R.T., and Rhodes M.E. Sexually diergic, dose-dependent hypothalamic-pituitary-adrenal axis responses to nicotine in a dynamic in vitro perfusion system. J. Pharmacol. Toxicol. Methods. 61:311-318, 2010.

    Gentile N.E., Andrekanic J.D., Karwoski T.E., Czambel R.K., Rubin R.T., and Rhodes M.E. Sexually diergic hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine infusion, and nicotine withdrawal by mecamylamine in rats. Brain Res Bull. 85:145-152, 2011.

    Rivardo M.G., Rhodes M.E., Camaione T.C., and Legg J.M. Stereotype threat leads to reduction in number of math problems women attempt. N. Amer. J. of Psychology. 13:5-16, 2011.

    Rubin R.T., McKlveen J.M., Fultz A.S., and Rhodes M.E. Basic principles of statistics: considerations for biomaterials engineers. In: An Introduction to Biomaterials, 2nd Edition, J.O. Hollinger (Ed.) CRC Press, Boca Raton, FL. 2012, pp. 175-189. (ISBN-10: 143981256X).

    Skwara A.J., Karwoski T.E., Czambel R.K., Rubin R.T., and Rhodes M.E. Influence of environmental enrichment on hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by mecamylamine in male and female rats. Behav. Brain Res. 234:1-10, 2012.

    Rupprecht D.P. and Rhodes M.E. Affixes are essential tools when teaching and studying pharmacological drug classes. Pharmacy Education. 14:109-115, 2014.

    Recent Presentations

    Moidel M.A., Fulton B.A., Czambel R.K., Rubin R.T., and Rhodes M.E. [sponsor] Hypothalamic-pituitary-adrenal axis responses to cholinergic drugs and hormones in an in vitro perfusion system. Society for Neuroscience, (San Diego) SFN ID: 315.1, Oct. 23-27, 2004.

    Rhodes M.E. [sponsor], Barkowski K.E., Teets B.E., Trice M.W., Czambel R.K., and Rubin R.T. Sexually diergic hypothalamic-pituitary-adrenal axis responses to single-dose nicotine alone and following continuous administration by osmotic mini-pumps in rats. FASEB J. (EB ‘06, San Francisco) Abstract: 6448; Program 175.6, 2006.

    Ingham B.A., and Rhodes M.E. An innovative in vitro perfusion system used to simulate HPA axis feedback in female and male rats. 27th Annual Undergraduate Biology Symposium for Western Pennsylvania. (Thiel College, Greenville) 2006.

    Rhodes M.E. [sponsor], Laco J.E., Evans B.B., Billings T.E., Czambel R.K., and Rubin R.T. HPA axis responses to oxotremorine in male and female M1 muscarinic receptor knockout and wild-type mice. Society for Neuroscience, (Atlanta) SFN ID: 563, Oct. 14-17, 2006.

    Rhodes M.E. [sponsor], McKlveen J.M., Wilson J.M., and Rubin R.T. Dose-dependent hypothalamic-pituitary-adrenal axis responses to nicotine in a dynamic in vitro perfusion system. Society for Neuroscience, (Washington, D.C.) SFN ID: 677.5, Nov. 15-19, 2008.

    Gentile N.E., McKlveen J.M., Czambel R.K., Karwoski T.E., Rubin R.T., and Rhodes M.E. Sexually diergic hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by single-dose mecamylamine in rats. FASEB J. (EB'09, New Orleans) Abstract: 4783; Program 941.10, 2009.

    Gentile N.E., McKlveen J.M., Andrekanic J.D., Czambel R.K., Karwoski T.E., Rubin R.T., and Rhodes M.E. Influence of environmental enrichment on hypothalamic-pituitary-adrenal responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by single-dose mecamylamine in rats. Society for Neuroscience, (Chicago) SFN ID: 84.16, Oct. 17-21, 2009.

    Rhodes M.E. [sponsor], Gentile N.E., McKlveen J.M., and Rubin R.T. Sexually diergic hypothalamic-pituitary-adrenal axis responses to various acetylcholinesterase inhibitors in an in vitro perfusion system. Society for Neuroscience, (Chicago) SFN ID: 84.18, Oct. 17-21, 2009.

    Skwara A.J., Gentile N.E., Andrekanic J.D., Karwoski T.E., Czambel R.K., Rubin R.T., and Rhodes M.E. [sponsor] Influence of environmental enrichment on sexually diergic hypothalamic-pituitary-adrenal responses to restraint stress following continuous nicotine by osmotic mini-pumps and nicotine withdrawal by single dose mecamylamine in rats. Society for Neuroscience, (San Diego) SFN ID: 792.7, Nov. 13-17, 2010.

    Rhodes M.E. [sponsor], Uddin M., Karwoski T.E., Czambel R.K., Rubin R.T. Estrous cycle effects on hypothalamic-pituitary-adrenal responses to single-dose nicotine, continuous nicotine by osmotic mini-pumps, and nicotine withdrawal by mecamylamine in female rats. Society for Neuroscience, (San Diego) SFN ID: 568.13, Nov. 9-13, 2013.

    Rhodes M.E. [sponsor], Harbaugh L.E., Rutkauskas J.A., Rubin R.T. Tissue hypothalamic-pituitary-adrenal axis responses to nicotine and mecamylamine following in vivo continuous nicotine administration and withdrawal. Society for Neuroscience, (Chicago) SFN ID: 313.06, Oct. 17-21, 2015.

    Current and Recent Projects

    Rhodes M.E. Adrenocorticotropic Hormone. In: Handbook of Stress Volume 2: Neuroendocrinology and Endocrinology. G. Fink (Ed.) Elsevier, Inc. Accepted for Publication, 2015.

    Professional Society Memberships

    American Association for the Advancement of Science (1996-present)

    American Society of Pharmacology and Experimental Therapeutics (1998-present)

    Society for Neuroscience (2003-present)