Built in 1969, the Chemistry Building is part of the five-building Science Center that consists of buildings devoted to four major areas of science – biology, life sciences, chemistry and physics/astronomy/computing. Undergraduate study in chemistry at Saint Vincent provides students with the background to pursue numerous career interests including graduate school, employment in a wide variety of industrial research positions, chemical sales and management, professional programs such as medical or law school, art conservation, science policy, journalism and forensics. Programs in Chemistry, Biochemistry and Environmental Chemistry are offered. Students who earn a bachelor of science degree in chemistry at Saint Vincent are certified by the American Chemical Society.

Just down the hill on the right is the Saint Vincent College Environmental Education Center and its distinctive mesocosm, an outdoor laboratory where artificial wetlands are part of the Monastery Run Mine Drainage Coalition's successful effort to cleanse the stream of impurities and coloration by filtering the water through layers of limestone.